Are you tired of living with chronic pain? You’re not alone. Chronic pain can last for months, even years, and it affects countless individuals worldwide. At our clinic, we understand the challenges you face and have developed a specialized treatment regimen tailored to the unique needs of chronic pain sufferers. Say goodbye to constant discomfort and embrace a life free from the limitations of pain.
Due to ketamine’s analgesic and anti-inflammatory properties, Ketamine Infusion Therapy can be many times better than opioid pain medication for managing the symptoms of chronic pain. It combats pain by acting against a specific chemical receptor known as N-methyl-D-aspartate, or NMDA, which is found in the nervous system, and helps modulate how the brain perceives pain. Ketamine also causes the body to decrease release of inflammatory mediators known as cytokines. The low-dose ketamine causes increased production and release of a protein in the brain, identifying and removing the neuronal synapses for pain while also creating new, healthy neuronal connections. It is much like resetting or rebooting a computer that has just crashed. Receiving meaningful relief from chronic pain and discomfort is the primary goal of this treatment.
Typically, the patients we treat who are experiencing chronic pain have not had much success with other pain medications or treatments. Conditions treated might include, but are not limited to:
Fibromyalgia is a disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory, and mood issues.
Complex Regional Pain Syndrome (CRPS), formerly known as Reflex Sympathetic Dystrophy (RSD), is a broad term describing excessive and prolonged pain due to inflammation that follows an injury or surgery.
Generalized Chronic Pain can be secondary to structural issues such as pinched nerves or inflammation due to excessive physical stress.
Ketamine Infusion Therapy can treat chronic pain better that would otherwise require large doses of narcotics or other painkillers. While these medications can help to relieve symptoms in the short term, they are not without their side effects. Unlike opioids, which make a person more sensitive to pain over time, Ketamine Infusion Therapy helps reduce the pain and rolls back the hypersensitivity caused by opioid therapy.
The Scenic City Neurotherapy’s pain-focused ketamine infusion protocols are individually tailored to fit each patient with the goal of minimizing inflammation and optimizing the way the brain perceives pain stimulus. This in turn allows the patient’s nervous system and perception of their physical environment to reset, making many chronic pain conditions more manageable and often in some cases providing complete relief without the need for a daily medication. The goal of Scenic City Neurotherapy is always to provide meaningful improvement in each patient’s quality of life.
Picture each opioid dose as blocking a pain receptor. Your body naturally releases an internal opioid to control everyday pain. This stops normal activities from causing pain. But when a severe injury occurs, internal opioids are not always enough, leading to external opioid prescriptions.
External opioids will relieve the injury pain by flooding pain receptors, but they will also trigger the creation of new pain receptors with each dose. Now you have even more pain receptors sending pain signals. Simultaneously, your body’s production of internal (natural) opioids diminishes, leading to an inability to experience happiness, well-being, or relief. Hence, the increased need for external opioids. The new pain receptors make everyday pains unmanageable, including any extra pain from excessive inflammation or later injuries.
Hyperalgesia, or hypersensitivity, is most often perceived as a migrating of the pain to other areas of the body. Say the pain starts in the foot, but over time it migrates up the leg or starts to mirror in the opposite limb. The migration and hypersensitivity can develop in patients with chronic pain who do not take external opioid medication. However, it is more common and progresses faster in those who take external opioids.
For the last few decades, it has been common knowledge that Opioid-Induced Hyperalgesia (OIH) is the primary culprit for the ever-growing number of patients requiring chronic opioid therapy. The attempt to limit opioid medication prescribing did not begin with the opioid addiction crisis. It began when we discovered that chronic opioid therapy will always cause the perception of pain to increase over time.
Opioids will lead to physical dependance even if you have taken your medications as prescribed. As a result, you will experience the same withdrawal as someone who abuses an opioid medication. This is not your fault, yet you are the only one who can change your situation.
Physical Therapy is an integral part of our treatment process. We understand pain often leads to inactivity or it has come from injury that leads to inactivity. Inactivity is one of the worst things you can do for your physical and mental health. When we do not use our muscles for an extended period of time, they will begin to deteriorate. This phenomenon is called “Disuse Syndrome,” and for those with chronic pain it can perpetuate the problem. Increasing muscle mass can help to insulate nerves and improving flexibility help you to navigate everyday activities with less pain. Non-opioid, non-narcotic medications may be a necessary component to optimize quality of life.
Yes. Opioids reverse any progress achieved through Minimally Stimulated Ketamine Infusion Therapy (MSKIT®). Choosing to continue or reverting back to opioid medications will cause the body to persist in generating additional pain receptors.
When chronic pain persists without a clear cause, our protocols function as a neuromodulatory reset, helping the central nervous system disengage maladaptive pain pathways and restore normal signaling.
In cases where pain persists despite optimal intervention, our protocols help quiet the pain response, giving patients space from suffering and improving their overall quality of life. This relief often helps patients maintain function and connection while navigating chronic or palliative conditions.
Most patients experience relief for 4–6 weeks before needing their first booster after stabilization. Over time, we often see a lower overall pain baseline. For example, someone who used to stay at a 6–7 may now top out at a 3–4 on their worst days.
Our treatments are individualized, and the goal isn’t just temporary relief. Ketamine helps improve your ability to self-manage pain, and we often recommend pairing treatment with physical therapy to build muscle support and improve long-term quality of life.
The most common Minimally Stimulated Ketamine Infusion Therapy (MSKIT®) protocol for pain involves six one-hour infusions over three weeks. Depending on your diagnosis and goals, your provider may suggest a different protocol.
Yes. Minimally Stimulated Ketamine Infusion Therapy (MSKIT®) for neuropathic pain is designed to remodulate the neuropathic signaling that starts in the brain, and reset the chronic inflammatory response in the body. However, ketamine alone is not enough to fully address Complex Regional Pain Syndrome (CRPS). At Scenic City Neurotherapy, we use a combination therapy to achieve effective relief.
Yes. When ketamine is administered intravenously at subanesthetic doses, we minimize risk and maximize efficacy. A longitudinal study followed patients receiving weekly treatment for 10 years, and no harm or dependency was reported.
Ketamine works on a specific receptor in the brain called the NMDA receptor, which plays a critical role in how pain is perceived and processed. By modulating glutamate, the brain’s primary excitatory neurotransmitter, ketamine helps reset the nervous system’s sensitivity to pain.
At Scenic City Neurotherapy, our Minimally Stimulated Ketamine Infusion Therapy (MSKIT) approach is designed to:
Unlike traditional medications that must be taken daily, ketamine infusions can create sustained improvements in pain perception and emotional resilience through direct neurological change.
Yes. Lidocaine blocks sodium channels, preventing nerve signaling and decreasing hypersensitivity to pain or hyperalgesia.
Ketamine increases neuroplasticity, your brain’s ability to form healthier patterns, helping reduce symptoms of depression, anxiety, chronic pain, PTSD, migraines, and other cognitive disorders.
Some patients notice subtle shifts within hours, while others begin to feel meaningful change gradually throughout the Stabilization Phase and beyond. There’s no standardized timeline, as individual responses naturally differ. Minimally Stimulated Ketamine Infusion Therapy (MSKIT®) opens the door for change, and your ongoing work helps guide how that change takes shape. Through neuroplasticity, MSKIT® opens a window where your brain can more easily build healthier patterns: new thoughts, behaviors, habits, and emotional responses. Actively practicing those healthier choices during this time is what makes the difference. The more you engage with these new patterns, the stronger and more sustainable they become.
Ketamine’s benefits can last weeks to several months, but duration varies from person to person. Results depend on the brain’s baseline health, how well new neural capacity is supported, and whether the patient continues healthy brain-care practices after treatment. Many patients maintain progress with periodic booster sessions as needed.
You’ll be in a private, calm environment with continuous monitoring. You will be given eye shades, a blanket if you’d like. You’ll dress comfy. Most people describe the feeling as light, floaty, or similar to nitrous oxide at the dentist. The feeling is temporary and a result of the ketamine.
Stabilization includes six infusions over three weeks. After that, booster sessions are scheduled based on your individual progress and goals.
Most people describe the feeling as light, floaty, or similar to nitrous oxide at the dentist.
You can't mess up Minimally Stimulated Ketamine Infusion Therapy (MSKIT®). The neurological cascade that ketamine initiates in your brain is a biological process that unfolds on its own. You cannot stop it, change it, or do it “wrong.” The vivid thoughts or emotions you may experience during a session are temporary, medication-driven experiences, similar to dreaming, and they do not determine your outcome or hold deeper meaning.
To learn if Ketamine Infusion is the right treatment option for you, contact us by calling for a free consultation or requesting one online today.
