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One-D Protocol for Depression

Fast. Focused. Science-Backed.

One-D Protocol for Depression

One-D Protocol for Depression

For those who need real relief now.

If you’ve tried everything and still don’t feel better, your brain may need a more targeted approach, not another prescription.

The Optimized Neuroplastogen Enhanced Depression (ONE-D) Protocol is an accelerated TMS therapy designed to deliver fast, effective relief for individuals struggling with depression, achieving over 90% response rates.

Developed by AMPA, the ONE-D Depression Protocol helps patients quickly regain clarity, control, and resilience, without long-term medication or trial-and-error.

What to Expect

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Speak with our clinical team to ensure you’re a good fit and get all your questions answered.
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Our TMS Director will contact you to schedule your treatment and review your intake paperwork, including any relevant medical history or considerations.  In the meantime, we encourage you to review our resources:

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Developed by AMPA, the protocol begins with plasticity priming, followed by 20 iTBS sessions over 9.5 hours, one every 30 minutes. 

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A patient-first experience designed to build on the neuroplastic gains from ONE-D, helping you clarify goals, access expert support, and take action toward lasting mental wellness. Be sure to check out our resources:

Traveling from Out of Town? We’re Here to Help.

Many of our patients travel to Chattanooga for our better treatment options. We’ll provide resources you need to make your trip smooth and supportive.
  • Hotel Recommendations — Quiet, clean, and comfortable options near our clinic
  • Local Dining — Healthy meals for before and after your treatment
  • Relaxing Spaces — Parks, walks, and peaceful places nearby
  • Transportation Info — Easy access from the airport, plus parking details

Review our travel and recovery guide to help you plan your stay. (Coming soon!)

Is ONE-D Right for You?

This TMS protocol may be a good fit if:

  • You’ve tried antidepressants with limited success
  • You want a safe, fast alternative backed by research
  • You’re ready to invest in your brain health and long-term well-being
  • You work odd hours, carry heavy responsibilities, or simply need an efficient solution

Start With a No-Cost Consult

We’ll answer your questions, explain the protocol, and help you plan your visit.

Why Patients Choose Scenic City Neurotherapy

  • Clinical expertise in neuroplasticity-driven care
  • Proven outcomes for treatment-resistant depression
  • Patients from across the country trust us for safe, science-backed treatment options
  • Precise 3D targeting with Stim-Guide neuronavigation for consistent, effective treatment

Take the First Step Toward Relief

Don’t wait for the next medication to maybe work.

Let’s take a different approach – one that’s focused on your brain, your life, and your results.