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(423) 228-0579
Request Consultation
423.228.0579

One-D Protocol for Depression

Fast. Focused. Science-Backed.

One-D Protocol for Depression

One-D Protocol for Depression

For those who need real relief now.

If you’ve tried everything and still don’t feel better, your brain may need a more targeted approach, not another prescription.

The Optimized Neuroplastogen Enhanced Depression (ONE-D) Protocol is an accelerated TMS therapy designed to deliver fast, effective relief for individuals struggling with depression, achieving over 90% response rates.

Developed by AMPA, the ONE-D Depression Protocol helps patients quickly regain clarity, control, and resilience, without long-term medication or trial-and-error.

What to Expect

Speak with our clinical team to ensure you’re a good fit and get all your questions answered. 

For dehydration-related pain or when recovery is needed after injury or surgery, IV fluids can help restore balance, reduce inflammation, and promote healing.

This powerful anti-inflammatory can provide relief from pain caused by inflammation, making it effective for conditions like acute back pain, joint pain, and muscle strain.

A patient-first experience designed to build on the neuroplastic gains from ONE-D, helping you clarify goals, access expert support, and take action toward lasting mental wellness. Be sure to check out our resources:

Traveling from Out of Town? We’re Here to Help.

Many of our patients travel to Chattanooga for our better treatment options. We’ll provide resources you need to make your trip smooth and supportive.

  • Hotel Recommendations — Quiet, clean, and comfortable options near our clinic
  • Local Dining — Healthy meals for before and after your treatment
  • Relaxing Spaces — Parks, walks, and peaceful places nearby
  • Transportation Info — Easy access from the airport, plus parking details

Review our travel and recovery guide to help you plan your stay. (Coming soon!)

Is ONE-D Right for You?

This TMS protocol may be a good fit if:

  • You’ve tried antidepressants with limited success
  • You want a safe, fast alternative backed by research
  • You’re ready to invest in your brain health and long-term well-being
  • You work odd hours, carry heavy responsibilities, or simply need an efficient solution

Start With a No-Cost Consult

We’ll answer your questions, explain the protocol, and help you plan your visit.
Request My No-Cost Consult

Why Patients Choose Scenic City Neurotherapy

  • Clinical expertise in neuroplasticity-driven care
  • Proven outcomes for treatment-resistant depression
  • Patients from across the country trust us for safe, science-backed treatment options
  • Precise 3D targeting with Stim-Guide neuronavigation for consistent, effective treatment

FAQS

TMS has been researched for over 30 years. In 2008, it received FDA approval in the U.S. for the treatment of major depressive disorder in adults who did not find relief from medications. Given its proven effectiveness, researchers continue investigating the benefits of TMS for various psychiatric and neurological conditions. At Scenic City Neurotherapy, we offer the rTMS, iTBS, and ONE-D protocols, as well as ketamine-assisted TMS protocols.

Those experiencing treatment-resistant depression who have not improved with medication often benefit from TMS.

TMS targets the prefrontal cortex, sending pulses that activate underperforming networks responsible for motivation and emotional balance. Over time, this rewires the brain toward healthier patterns.

Most people feel a tapping sensation on the scalp during treatment and have no downtime afterward. Side effects are typically mild and may include brief scalp sensitivity or a light headache.

Yes. TMS is a non-medication, evidence-based treatment that uses gentle magnetic stimulation to improve mood, focus, and overall brain health without systemic side effects.

At Scenic City Neurotherapy, patients report 90% or greater remission of their depressive symptoms when completing TMS using either the SNT or the ONE-D treatment approaches.

At Scenic City Neurotherapy in Chattanooga, TMS is provided in a controlled, evidence-based setting designed to help patients improve long-term brain health and reduce depressive symptoms.

Transcranial Magnetic Stimulation (TMS) is insurance-reimbursable, and we help patients navigate that process. Insurance does not typically cover Minimally Stimulated Ketamine Infusion Therapy (MSKIT®), though many patients use health savings accounts, and we offer flexible payment options through CareCredit. Scenic City Neurotherapy also provides the SCN Service Program, which offers scholarships for those who qualify. Additionally, we are in network with Veteran Affairs, and veterans only need a VA referral to begin care. Our team will walk you through every option available and provide any documentation needed for reimbursement attempts.

Take the First Step Toward Relief

Don’t wait for the next medication to maybe work.

Let’s take a different approach – one that’s focused on your brain, your life, and your results.

REQUEST CONSULTATION